David R. Thorburn

Geneticist

Male📍 Melbourne

About of David R. Thorburn

David R. Thorburn is a Geneticist based in Flemington Road, Melbourne, VIC, Australia.


As a geneticist, David helps families understand conditions that can be passed through genes. These can show up early in life, or later, and they can affect many parts of the body at once. In many cases, the clues are in how symptoms start, how they change over time, and what runs in a family.


David works with people who may have inherited metabolic disorders and mitochondrial conditions. You might hear names like Leigh Syndrome, MELAS, or VLCAD deficiency. He also looks at other genetic causes of long-term health issues, including nerve and muscle problems, movement changes, hearing loss, and growth or development concerns. Some patients may have epilepsy or seizures, ongoing weakness or low muscle tone, or trouble with balance and coordination.


Depending on what is going on, the focus can include heart and breathing issues, liver problems, and feeding or gut symptoms. At times, there can be complex mixes like lactic acidosis, metabolic acidosis, or cardiomyopathy, plus learning and development impacts. There are also conditions tied to hormones and development, like Turner Syndrome or premature ovarian failure.


To help with answers, David may use genetic testing and clinical reviews, and he can work with further investigations when they are needed. This can include processes such as tissue biopsy in some cases, alongside tests guided by symptoms and family history.


For people dealing with symptoms like tremor or unusual movements, recurrent episodes such as diabetic ketoacidosis, or longer-term neurological changes, having a clear genetic explanation can make a real difference. It can also help teams plan follow-up, manage risk, and understand what might come next.


David’s role sits at the point where careful diagnosis meets practical next steps. Over time, that means working closely with patients and carers, keeping things clear, and making sure the genetics side of the story is understood as well as it can be.

Services & Conditions Treated

Leigh SyndromeMitochondrial Complex 1 DeficiencySengers SyndromeCoenzyme Q Cytochrome C Reductase DeficiencyCytochrome C Oxidase DeficiencyHolocarboxylase Synthetase DeficiencyLactic AcidosisMohr-Tranebjaerg SyndromeMultiple Carboxylase DeficiencyPerrault SyndromeSideroblastic AnemiaAlpers-Huttenlocher SyndromeAlternating Hemiplegia of ChildhoodAnemiaCACH SyndromeCardiomyopathyCerebellar HypoplasiaCongenital CataractDiabetic KetoacidosisDiabetic NephropathyDrug Induced DyskinesiaEpilepsyEpilepsy in ChildrenHearing LossHemiplegiaHereditary AtaxiaHypotoniaInfant Respiratory Distress SyndromeInfantile Axonal NeuropathyIntersexLeukodystrophyLiver FailureMELAS SyndromeMetabolic AcidosisMitochondrial Neurogastrointestinal Encephalopathy DiseaseOptic Nerve AtrophyPelizaeus-Merzbacher DiseasePeripheral NeuropathyPremature Ovarian FailureSeizuresShort Stature (Growth Disorders)Tissue BiopsyTumefactive Multiple SclerosisTurner SyndromeVery Long-Chain Acyl-CoA Dehydrogenase (VLCAD) DeficiencyWest SyndromeWilson Disease

Publications

1 total

Atf3 controls transitioning in female mitochondrial cardiomyopathy as identified by spatial and single-cell transcriptomics.

Science advances • April 04, 2025

Frequently Asked Questions

What services does Dr David R. Thorburn offer?
Dr Thorburn provides genetic services related to a wide range of mitochondrial and metabolic conditions, including disorders like MELAS, Coenzyme Q deficiency, Sengers syndrome, Leigh syndrome, and related genetic and neurological issues.
Which conditions can I discuss with Dr Thorburn?
You can discuss conditions such as mitochondrial disorders, leukodystrophy, various metabolic diseases, epilepsy with metabolic causes, anemia, hearing and vision issues, growth and developmental concerns, and related syndromes listed in his scope.
Where is Dr Thorburn’s clinic located?
The practice is in Melbourne, at Flemington Road, VIC, Australia.
How can I book an appointment with Dr Thorburn?
Appointments are arranged through his Melbourne practice. Please contact the clinic to organise a consult.
What kinds of patient concerns are suitable for a consult with a geneticist like Dr Thorburn?
Concerns around hereditary or inherited conditions, suspected mitochondrial disorders, metabolic issues, and developmental or neurological symptoms that may have a genetic basis are appropriate to discuss.
Is there information about the types of tests or biopsies used?
Details about tests, such as tissue biopsy or genetic assessments, can be discussed during a consult. The listed services cover many diagnostic and management areas in genetics.

Contact Information

Flemington Road, Melbourne, VIC, Australia

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