Mark Clendenning is a geneticist who works out of 305 Grattan Street, Parkville, VIC 3010, Australia.
Hereditary cancer matters. In many cases, it’s not just about one person’s health, but what might run in a family. Mark helps people and families who’ve been told they may have a higher risk linked to genes. He also looks at patterns that can show up in bowel health, womb (endometrial) health, and some types of brain tumours.
His clinical work focuses on conditions such as familial colorectal cancer and Lynch syndrome. He also helps with familial adenomatous polyposis, and Turcot syndrome, where there can be more than one body area involved. At times, this can be connected to mosaicism too, which is when genetic change is present in some cells. Mark also supports people who have had cancers like endometrial cancer, and he may be involved when there are concerns around brain tumours. In some situations, he helps make sense of skin findings like sebaceous adenoma, especially when they fit a known inherited pattern.
Care usually starts with understanding the family story and looking at what tests and results mean in real life. Genetic results can feel confusing, so he aims to explain things in plain language and help people think through what’s next. That might include guidance around ongoing checks and planning for the future, often alongside other health professionals.
Mark works with the bigger picture of colorectal cancer risk, not just one scan or one result. He also supports the practical side of care, including planning and follow-up steps that can help people stay on top of things. He stays across new research and updates in hereditary cancer care, because these fields keep moving. If you’re dealing with a family history of cancer and you’re unsure where to start, he can help you sort out the genetic side of the story.
